An Introduction on Tissue Engineering
Soheila Ali Akbari Ghavimi, BA; *Mehran Solati Hashjin, PhD; **Mohammad Hossein Ebrahimzadeh, MD
Abstract Tissue engineering is a science to generate biological substitutes for regeneration, preservation and better operation of damaged tissues. Main components of tissue engineering are scaffolds, cells and growth factors. Also, bioreactors seem to be one of the fundamental parts. Scaffold is a 3D structure as a framework to support cell growth and extra cellular matrix deposition. Cells penetrate to scaffolds and grow, differentiate, proliferate and migrate according to physical and chemical signals. If the environment is appropriate for cells, they deposit ECM and new tissue will be formed. Tissue engineering science is to fabricate scaffolds which are suitable for cellular homing, to create and retain appropriate environment for cell maintenance and to control all the parameters which is important to generate new tissues.