Effect of Alveolar Ridge Preservation with PDFDBA on Orthodontic Tooth Movement Rate, Formation of Gingival Invagination and Root Resorption: A Randomized, Controlled Pilot Study

ABSTRACT
Tooth extraction results in resorptive remodeling of the alveolar bone, but alveolar ridge preservation procedure maintains the original shape of the extraction socket. This may be beneficial for space closure by orthodontic tooth movement (OTM). In the current pilot study for randomized controlled clinical trial the effect of alveolar ridge preservation with partial demineralized freezedried bone allograft (PDFDBA) on OTM rate, formation of gingival invagination and root resorption was evaluated. Both mandibular first premolars of 6 patients were extracted due to orthodontic treatment. In a split-mouth study design, alveolar ridge preservation was performed on one side, while the other side served as a control and the extraction socket healed naturally. After 6 weeks of healing period, the canines were moved to the extraction site to close the extraction space. Eight weeks later, the amount of OTM was measured. After space closure, the extraction sites were examined for the presence of gingival invagination. Root resorption was evaluated on digital panoramic radiographs. Photographs were taken for documentation. There was no significant difference in OTM rate between the ridge preserved areas and naturally healed sockets. Gingival invagination formed in 5 of 6 naturally healed sockets; none of the ridge preserved areas showed formation of gingival invagination. No root resorption was observed in any of the teeth adjacent to the extraction sites. Alveolar ridge preservation with PDFDBA has no effect on the rate of OTM and root resorption but prevents formation of gingival invagination during orthodontic space closure